In this course you will learn what is structural bioinformatics all about and get an introduction of all the major areas of structural bioinformatics. Structural Bioinformatics is an interdisciplinary field that deals with the three dimensional structures of bio-molecules. It attempts to model and discover the basic principles underlying biological machinery at the molecular level. It is based on the assumption that 3D structural information of a biological system is the core to understanding its mechanism of action and function. Structural bioinformatics combines applications of physical and chemical principles with algorithms from computational science.